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Home / Journal of Asian Natural Products Research, Volume 14, Number 4

Cichorins B and C: two new benzo-isochromenes from Cichorium intybus

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Two new benzo-isochromenes, named cichorins B (1) and C (2), were isolated from Cichorium intybus. The structures of the new compounds were elucidated by detailed spectroscopic analysis such as 1H, 13C NMR, COSY, HMQC, HMBC, and HR-EI-MS. Relative configurations of asymmetric centers of cichorins B and C were determined by the analysis of the 1H NMR coupling constants together with the 2D NOESY and 1D NOE experiments as well as from value.

Keywords: Asteraceae; Cichorium intybus; benzo-isochromene; cichorins

Document Type: Research Article

Affiliations: 1: Department of Biological Sciences and Chemistry,College of Arts and Sciences, University of Nizwa, Birkat Al-MouzNizwa,616, Sultanate of Oman 2: Department of Chemistry,Kohat University of Science and Technology, Kohat,Khyber Pakhtunkhwa, Pakistan 3: Department of Chemistry,The Islamia University of Bahawalpur, Baghdad Campus-ul-Jadid, Bahawalpur,63000, Pakistan 4: Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan 5: NUST Center of Virology and Immunology, National University of Science and Technology, H-12, Islamabad, Pakistan 6: Department of Chemistry,Islamia College Peshawar, University of Peshawar, Peshawar,Khyber Pakhtunkhwa, Pakistan 7: Department of Chemistry,Post Graduate College Parachinar, Kurram Agency, Khyber Pakhtunkhwa, Pakistan

Publication date: 01 April 2012

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