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Home / Psychiatric Genetics, Volume 26, Number 3

Long noncoding RNAs in psychiatric disorders

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Long noncoding RNAs (lncRNAs) are nonprotein coding transcripts longer than 200 nucleotides. Many of these lncRNAs have regulatory functions and have recently emerged as major players in governing fundamental biological processes. Here, we review the definition, distribution, identification, databases, analysis, classification, and functions of lncRNAs. We also discuss the potential roles of lncRNAs in the etiological processes of psychiatric disorders and the implications for clinical diagnosis and treatment.

Keywords: lncRNAs; psychiatric disorders; regulation

Document Type: Research Article

Affiliations: 1: Biological Psychiatry Research Center, Beijing Huilongguan Hospital, Beijing, China 2: Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, Tennessee 3: Department of Psychology, Nevada Institute of Personalized Medicine, University of Nevada, Las Vegas, Neveda, USA 4: Departments of Psychiatry 5: Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut

Publication date: 01 June 2016

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