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Early antiretroviral therapy initiation in west Africa has no adverse social consequences: a 24-month prospective study

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A retrospective cohort analysis comparing the efficacy of boosted protease inhibitor-based and efavirenz-based combination antiretroviral therapy in treatment-naïve people living with HIV with baseline resistance found that efavirenz-based treatment led to a shorter mean time to undetectable viral load. A higher proportion of patients with nonnucleoside reverse transcriptase inhibitor related baseline resistance mutations in the efavirenz-treatment group achieved an undetectable viral load at both 6 and 12 months post-treatment initiation, compared with the boosted protease-inhibitor-treatment group.

Supplementary content: http://links.lww.com/QAD/A930.

Document Type: Research Article

Affiliations: 1: Imperial College London, South Kensington Campus 2: Chelsea and Westminster Hospital NHS Foundation Trust 3: Barts Healthcare NHS Trust, London, UK. 4: Imperial College London, South Kensington Campus, Chelsea and Westminster Hospital NHS Foundation Trust

Publication date: 17 July 2016

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