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Nicotine Intake, Dependence, and Characteristics of Electronic Cigarette and Dual Users

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Objectives: We examined nicotine exposure, level of dependence, reasons for vaping, use patterns, and device characteristics to increase understanding of electronic cigarette and dual tobacco cigarette (TC) users and to help inform potential health benefits and risks. Methods: We had 68 exclusive electronic cigarette (EEC) and 100 dual users (DU) complete questionnaires and provide saliva for cotinine measurement. Results: The mean age of participants was 34 years and 65% were male. Among DUs, 31 were light DUs (≤5 cigarettes per day (CPD)) and 69 were heavy DUs (>5 CPD). Cotinine levels were not significantly different for EEC users and DUs, although heavy DUs had significantly lower cotinine than light DUs. EEC users had a shorter time to first vape than DUs. Compared to DUs, EEC users were more likely to vape daily, to vape to reduce health risk from tobacco cigarettes (amongst other reasons), to use a second- or third-generation device and to use lower nicotine concentration e-liquids. Conclusions: Dual and EEC users had similar daily nicotine intake, and DUs' time to first cigarette was similar with EEC users' time to first vape, suggesting a similar degree of dependence.
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Document Type: Research Article

Publication date: January 1, 2019

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  • Tobacco Regulatory Science (Electronic ISSN 2333-9748) is a rigorously peer-reviewed online scientific journal for the dissemination of research relevant to the regulation of tobacco products. The journal content includes a broad array of research domains, including chemistry, biology, behavior, community, and population-level surveillance and epidemiology, as well as knowledge syntheses (eg, meta-analyses or state-of-the-art reviews) and analytic modeling. All articles describe the policy relevance of the research outcomes. Given the global nature of tobacco regulation, particularly as a result of international and national policies, Tobacco Regulatory Science publishes high quality research that is relevant to global regulatory needs and requirements. Tobacco Regulatory Science is published electronically 6 times per year.
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