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Circadian Puffing Behavior and Topography among E-cigarette Users

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Objectives: The aim of this study was to examine puffing behavior and topography over 24 hours among regular electronic cigarette (e-cigarette) users. Methods: Twenty-four adult e-cigarette users (15 males) vaped their personal e-cigarettes ad-lib over the course of 24 hours. Participants took each puff via calibrated CReSS pocket topography monitors. We analyzed the number of puffs per day per session, mean puff volume, mean puff flow rate, mean duration of puff, and mean interval between puffs. Results: Over 24 hours, participants took an average of 156.2 ± 10.3 puffs, clustered in 10.2 ± 7.9 puffs per puffing session with an average puff interval of 15.4 ± 22.0 seconds. A single puff lasted on average 3.0 ± 1.2 seconds, had a volume of 73.4 ± 51.5 ml, and was taken with the average flow rate of 24.7 ± 10.2 ml/seconds. Conclusions: There is substantial variability among e-cigarette users in the way they puff on these devices. When e-cigarette aerosol is generated for laboratory studies, there is a need for validated puffing protocols that not only reflects the most-common pattern but also intensive puffing behaviors observed among some e-cigarette users.
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Document Type: Research Article

Publication date: September 1, 2018

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  • Tobacco Regulatory Science (Electronic ISSN 2333-9748) is a rigorously peer-reviewed online scientific journal for the dissemination of research relevant to the regulation of tobacco products. The journal content includes a broad array of research domains, including chemistry, biology, behavior, community, and population-level surveillance and epidemiology, as well as knowledge syntheses (eg, meta-analyses or state-of-the-art reviews) and analytic modeling. All articles describe the policy relevance of the research outcomes. Given the global nature of tobacco regulation, particularly as a result of international and national policies, Tobacco Regulatory Science publishes high quality research that is relevant to global regulatory needs and requirements. Tobacco Regulatory Science is published electronically 6 times per year.
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