Levetiracetam

THE INCIDENCE OF NEONATAL seizures varies according to gestational age, weight, and cause. Seizures occur in an estimated 1.0-3.5 per 1,000 term infants¹ with an increased incidence of 10-130/1,000 in preterm infants.² Most neonatal seizures have a specific cause.³ Hypoxic-ischemic encephalopathy has been identified as the most common etiology associated with neonatal seizures, accounting for 50-60 percent of the cases.⁴ Table 1 outlines common causes of neonatal seizures. Early recognition of seizures and appropriate treatment is vital in preventing multiorgan dysfunction and permanent brain damage.