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Chest X-Ray Findings in Arteriovenous Malformation of the Great Vein of Galen

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THE MOST COMMON NEONATAL intracranial arteriovenous malformation (AVM) is an aneurysm of the vein of Galen.1 This aneurysm presents in the immediate neonatal period in 90 percent of cases and predominantly affects males.2 The primary abnormality consists of multiple arterial feeding vessels joined via a nidus (central nucleus) to draining veins. The arterial vessels vary in structure from normally differentiated arteries to primitive vessels. Histology reveals arterial vessels that are dysplastic, dilated, and tortuous, with hyperplastic and disorganized smooth muscle fibers. The internal elastic lamina of these vessels is fragmented or absent. The veins are dysplastic with anomalous veinlike channels; reactive muscular hyperplasia; and degenerative changes of fibrosis, atrophy, thrombi, and calcification.3

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Document Type: Research Article

Publication date: April 1, 2000

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