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Free Content The Fruitless Search for Schizophrenia Genes

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This article reviews recent events in the continuing unsuccessful efforts to discover genes presumed to cause schizophrenia. Researchers and reviewers reporting these events usually downplay the continuing failures, and speak in glowing terms of discoveries they believe will occur in the future. However, schizophrenia molecular genetic research is based on the mistaken belief that previous kinship studies of families, twins, and adoptees have definitively established the genetic basis of schizophrenia. Thus, researchers rarely consider the possibility that they have found no schizophrenia genes because there are no schizophrenia genes. In this article, I argue that researchers should take a critical look into the original schizophrenia family, twin, and adoption research upon which they base their work. This might lead them to consider the possibility that the main premise of their work, that schizophrenia genes must exist, is false.
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Document Type: Journal Article

Affiliations: La Familia Counseling Service Hayward, CA

Publication date: January 1, 2004

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