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Open Access The Life Sciences Mass Spectrometry Research Unit

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The Life Sciences Mass Spectrometry (LSMS) research unit focuses on the development of novel analytical workflows based on innovative mass spectrometric and software tools for the analysis of low molecular weight compounds, peptides and proteins in complex biological matrices. The present article summarizes some of the recent work of the unit: i) the application of matrix-assisted laser desorption/ionization (MALDI) for mass spectrometry imaging (MSI) of drug of abuse in hair, ii) the use of high resolution mass spectrometry for simultaneous qualitative/quantitative analysis in drug metabolism and metabolomics, and iii) the absolute quantitation of proteins by mass spectrometry using the selected reaction monitoring mode.

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Keywords: MASS SPECTROMETRY

Document Type: Research Article

Affiliations: 1: School of Pharmaceutical Sciences University of Geneva, University of Lausanne Life Sciences Mass Spectrometry Quai Ernest-Ansermet, 30 CH-1211 Geneva 4, Switzerland. [email protected] 2: School of Pharmaceutical Sciences University of Geneva, University of Lausanne Life Sciences Mass Spectrometry Quai Ernest-Ansermet, 30 CH-1211 Geneva 4, Switzerland

Publication date: May 1, 2012

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  • International Journal for Chemistry and Official Membership Journal of the Swiss Chemical Society (SCS) and its Divisions

    CHIMIA, a scientific journal for chemistry in the broadest sense, is published 10 times a year and covers the interests of a wide and diverse readership. Contributions from all fields of chemistry and related areas are considered for publication in the form of Review Articles and Notes. A characteristic feature of CHIMIA are the thematic issues, each devoted to an area of great current significance.

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