Skip to main content
padlock icon - secure page this page is secure

Open Access Extending Timescales and Narrowing Linewidths in NMR

Download Article:
 Download
(PDF 221.3 kb)
 
Among the different fields of research in nuclear magnetic resonance (NMR) which are currently investigated in the Laboratory of Biomolecular Magnetic Resonance (LRMB), two subjects that are closely related to each other are presented in this article. On the one hand, we show how to populate long-lived states (LLS) that have long lifetimes T LLS which allow one to go beyond the usual limits imposed by the longitudinal relaxation time T 1. This makes it possible to extend NMR experiments to longer time-scales. As an application, we demonstrate the extension of the timescale of diffusion measurements by NMR spectroscopy. On the other hand, we review our work on long-lived coherences (LLC), a particular type of coherence between two spin states that oscillates with the frequency of the scalar coupling constant J IS and decays with a time constant T LLC. Again, this time constant T LLC can be much longer than the transverse relaxation time T 2. By extending the coherence lifetimes, we can narrow the linewidths to an unprecedented extent. J-couplings and residual dipolar couplings (RDCs) in weakly-oriented phases can be measured with the highest precision.

30 References.

No Supplementary Data.
No Article Media
No Metrics

Keywords: DIFFUSION; LONG-LIVED COHERENCES; LONG-LIVED STATES; NMR; UBIQUITIN

Document Type: Research Article

Affiliations: 1: Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques, Laboratoire de Résonance Magnétique Biomoléculaire, Batochime, CH-1015 Lausanne, Switzerland 2: Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques, Laboratoire de Résonance Magnétique Biomoléculaire, Batochime, CH-1015 Lausanne, Switzerland; Université Paris Descartes, UMR 8601 CNRS, 45, rue des Saints-Pères 75006, Paris, France 3: Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques, Laboratoire de Résonance Magnétique Biomoléculaire, Batochime, CH-1015 Lausanne, Switzerland; Département de Chimie, Ecole Normale Supérieure, 24 Rue Lhomond, 75231, Paris Cedex 05, France

Publication date: September 1, 2011

More about this publication?
  • International Journal for Chemistry and Official Membership Journal of the Swiss Chemical Society (SCS) and its Divisions

    CHIMIA, a scientific journal for chemistry in the broadest sense, is published 10 times a year and covers the interests of a wide and diverse readership. Contributions from all fields of chemistry and related areas are considered for publication in the form of Review Articles and Notes. A characteristic feature of CHIMIA are the thematic issues, each devoted to an area of great current significance.

  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Information for Advertisers
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more