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Open Access Biomaterials for Injectable Therapeutic Implants

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Injectable biomaterials that have the ability to form semi-solid implants in situ are of keen interest for therapeutic applications. The materials may be used to fill in pathological vascular spaces or be designed to possess functional properties such as being radiopaque for an improved visibility during image-guided minimally invasive interventions, or induce a localized biological activity. Among the variety of solidification principles that may be used to produce implants in situ, the precipitation of water-insoluble polymers driven by solubility changes shows some particular features that may be valuable for specific therapeutic applications. This paper reviews some of the applications of these implant-forming biomaterials in interventional radiology, urology, and oncology.

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Keywords: EMBOLIZATION; INJECTABLE BIOMATERIALS; INTERVENTIONAL PROCEDURES; ONCOLOGY; POLYMERIC IMPLANTS; UROLOGY

Document Type: Research Article

Publication date: June 1, 2005

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  • International Journal for Chemistry and Official Membership Journal of the Swiss Chemical Society (SCS) and its Divisions

    CHIMIA, a scientific journal for chemistry in the broadest sense, is published 10 times a year and covers the interests of a wide and diverse readership. Contributions from all fields of chemistry and related areas are considered for publication in the form of Review Articles and Notes. A characteristic feature of CHIMIA are the thematic issues, each devoted to an area of great current significance.

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