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Open Access Application of Mass Spectrometry for Quantitative and Qualitative Analysis in Life Sciences

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Due to its ability to analyze macromolecules, as well as polar and thermally labile low molecular weight compounds, mass spectrometry has become a very important tool in bioanalysis in recent years. The Life Sciences Mass Spectrometry Laboratory (LSMS) at the School of Pharmaceutical Sciences, University of Geneva, opened on April 1st, 2002. Its work is focused on the development and application of mass spectrometry for the qualitative and quantitative analysis of low molecular compounds and macromolecules present in biological fluids, tissues, organisms or cells. The instruments used for the research include: single quadrupole, triple quadrupole and hybrid MS instruments such as triple quadrupole linear ion traps; equipped with electrospray, nanoelectrospray, atmospheric pressure chemical ionization and matrix-assisted laser desorption.

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Keywords: CHIP-BASED INFUSION; MALDI; MASS SPECTROMETRY; METABOLITE PROFILING; NON-COVALENT COMPLEX

Document Type: Research Article

Publication date: June 1, 2005

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  • International Journal for Chemistry and Official Membership Journal of the Swiss Chemical Society (SCS) and its Divisions

    CHIMIA, a scientific journal for chemistry in the broadest sense, is published 10 times a year and covers the interests of a wide and diverse readership. Contributions from all fields of chemistry and related areas are considered for publication in the form of Review Articles and Notes. A characteristic feature of CHIMIA are the thematic issues, each devoted to an area of great current significance.

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