Tailoring the Adhesion of Polymers using Plasma for Biomedical Applications: A Critical Review
This paper reviews the recent advances in the field of polymer adhesion aided by plasma in biomedical field. The first part of the paper discusses the latest techniques available to improve the adhesion properties of polymers with a special focus on their application in biomedicine. The mechanism of plasma surface modification has been described in the subsequent section. Methods by which plasma can enhance the adhesiveness of polymers have been divided into three categories: plasma surface modification, plasma deposition, and plasma nano/micro-structuring. Special attention has been given to the enhancement of cell adhesion and proliferation, immobilization of bioactive molecules, and reduction in protein adsorption and platelet adhesion. The concluding section briefly compares all the techniques and sheds light onto some of the major challenges faced by this technology.
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