Skip to main content

Open Access Integrating hepatitis C treatment into multidrug-resistant TB care

Download Article:
BACKGROUND: Direct-acting antivirals (DAAs) are not widely used for patients with chronic hepatitis C virus (HCV) infection and multidrug- or rifampicin-resistant TB (MDR/RR-TB). We describe the implementation aspects of a new integrated model of care in Armenia and the perceptions of the healthcare staff and patients.

METHODS: We used qualitative methods, including a desktop review and semi-structured individual interviews with healthcare staff and with patients receiving HCV and MDR/RR-TB treatment.

RESULTS: The new integrated model resulted in simplified management of HCV and MDR/RR-TB at public TB facilities. Training on HCV was provided for TB clinic staff. All MDR/RR-TB patients were systematically offered HCV testing and those diagnosed with HCV, offered treatment with DAAs. Treatment monitoring was performed by TB staff in coordination with a hepatologist. The staff interviewed had a positive opinion of the new model. They suggested that additional training should be provided. Most patients were fully satisfied with the care received. Some were concerned about the increased pill burden.

CONCLUSION: Integrating HCV treatment into MDR/ RR-TB care was feasible and appreciated by patients and staff. This new model facilitated HCV diagnosis and treatment among people with MDR/RR-TB. Our results encourage piloting this model in other settings.

Keywords: DAAs; HCV; MDRTB; direct-acting antivirals; integrated care

Document Type: Research Article

Affiliations: 1: Médecins Sans Frontières (MSF), Yerevan, Armenia 2: Médecins Sans Frontières (MSF), Yerevan, Armenia, Epicentre, Paris, France 3: Epicentre, Paris, France 4: Médecins Sans Frontières (MSF), Yerevan, Armenia, National Tuberculosis Control Centre, Ministry of Health, Yerevan, Armenia 5: National Tuberculosis Control Centre, Ministry of Health, Yerevan, Armenia 6: Médecins Sans Frontières (MSF), Yerevan, Armenia, Ministry of Health, Yerevan, Armenia 7: MSF, Paris, France

Publication date: June 21, 2022

More about this publication?
  • Public Health Action (PHA), The Union's quarterly Open Access journal, welcomes the submission of articles on operational research. It publishes high-quality scientific research on health services, providing new knowledge on how to improve access, equity, quality and efficiency of health systems and services.

    The Editors will consider any manuscript reporting original research on quality improvements, cost-benefit analysis, legislation, training and capacity building, with a focus on all relevant areas of public health (e.g. infection control, nutrition, TB, HIV, vaccines, smoking, COVID-19, microbial resistance, outbreaks etc).

  • Editorial Board
  • Information for Authors
  • International Journal of Tuberculosis and Lung Disease
  • Public Health Action
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content