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Open Access Delivery of TB preventive therapy to incarcerated people living with HIV in southern African correctional facilities

TB preventive treatment (TPT) is recommended for high-risk and hard-to-reach populations such as incarcerated people living with HIV (PLHIV). To assess implementation of TPT delivery in correctional settings, we conducted an exploratory analysis of data from a multisite cohort study in South Africa and Zambia. From 975 participants, 648 were screened for TB, and 409 initiated TPT mostly within a month after initiation of antiretroviral therapy (190/409, 46.5%). We observed a median gap of one month (IQR 0.6–4.7) in TPT delivery to incarcerated PLHIV. Future research should examine standardised quality improvement tools and new strategies such as short-course regimens to improve TPT initiation in this population.

Keywords: South Africa; TPT cascade; Zambia; inmates; short-course regimens

Document Type: Research Article

Affiliations: 1: The Aurum Institute, Parktown, Johannesburg, South Africa 2: Centre for Infectious Disease Research in Zambia, Lusaka, Zambia, School of Population Health, University of New South Wales, Sydney, NSW, Australia 3: TB HIV Care, Cape Town, South Africa 4: London School of Tropical Hygiene & Medicine, London, UK 5: The Aurum Institute, Parktown, Johannesburg, South Africa, Johns Hopkins University, Baltimore, MD, USA 6: Centre for Infectious Disease Research in Zambia, Lusaka, Zambia, Institute for Global Health & Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC, USA 7: The Aurum Institute, Parktown, Johannesburg, South Africa, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa

Publication date: 21 December 2021

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