Skip to main content
padlock icon - secure page this page is secure

Open Access Influence of the 2014–2015 Ebola outbreak on the vaccination of children in a rural district of Guinea

Download Article:
(PDF 308.9 kb)
Setting: All health centres in Macenta District, rural Guinea.

Objective: To compare stock-outs of vaccines, vaccine stock cards and the administration of various childhood vaccines across the pre-Ebola, Ebola and post-Ebola virus disease periods.

Design: This was an ecological study.

Results: Similar levels of stock-outs were observed for all vaccines (bacille Calmette–Guérin [BCG], pentavalent, polio, measles, yellow fever) in the pre-Ebola and Ebola periods (respectively 2760 and 2706 facility days of stock-outs), with some variation by vaccine. Post-Ebola, there was a 65-fold reduction in stock-outs compared to pre-Ebola. Overall, 24 facility-months of vaccine stock card stock-outs were observed during the pre-Ebola period, which increased to 65 facility-months of stock-outs during the Ebola outbreak period; no such stock-out occurred in the post-Ebola period. Apart from yellow fever and measles, vaccine administration declined universally during the peak outbreak period (August–November 2014). Complete cessation of vaccine administration for BCG and a prominent low for polio (86% decrease) were observed in April 2014, corresponding to vaccine stock-outs. Post-Ebola, overall vaccine administration did not recover to pre-Ebola levels, with the highest gaps seen in polio and pentavalent vaccines, which had shortages of respectively 40% and 38%.

Conclusion: These findings highlight the need to sustain vaccination activities in Guinea so that they remain resilient and responsive, irrespective of disease outbreaks.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: SORT IT; health service utilisation; health systems strengthening; operational research; prevention

Document Type: Research Article

Affiliations: 1: Department of Public Health, Gamal University of Conakry, Conakry, Guinea 2: Department of Public Health, Gamal University of Conakry, Conakry, Guinea, Woman and Child Health Research Centre, Institute of Tropical Medicine, Antwerp, Belgium 3: University of Gondar, Gondar, Ethiopia 4: Bixby Center for Global Reproductive Health, University of California, San Francisco, California, USA 5: Centre National de Formation et de Recherche en Santé Rurale de Maferinyah, Forecariah, Guinea 6: International Union Against Tuberculosis and Lung Disease, Paris, France 7: Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan 8: Department of Gynecology-Obstetrics, Gamal University of Conakry, Conakry, Guinea 9: Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium 10: Médecins Sans Frontières, Brussels Operational Centre (LuxOR), Luxembourg

Publication date: June 21, 2017

More about this publication?
  • Public Health Action (PHA), The Union's quarterly open access on-line journal, provides a platform for its mission 'Health solutions for the poor'. PHA addresses the need for show-casing operational research that addresses issues in health systems and services. It publishes high-quality scientific research that provides new knowledge to improve access, equity, quality and efficiency of health systems and services.

  • Editorial Board
  • Information for Authors
  • International Journal of Tuberculosis and Lung Disease
  • Public Health Action
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more