Evaluation of the implementation of the Xpert® MTB/RIF assay in Fiji
Objectives: To determine 1) the number of Xpert tests performed in each centre, 2) the association between sputum quality and Xpert results, 3) the agreement of Xpert with acid-fast bacilli (AFB) smear microscopy and TB culture and 4) error rates.
Design: Retrospective review of records.
Results: A total of 415 Xpert tests were performed in the study period.
Conclusion: Although a good correlation between Xpert and the two tests were shown in the study, Xpert should not replace the routine first-line TB diagnostic tests used in Fiji for reasons related to logistics and sustainability. A further evaluation of the assay's performance is required over a longer time period to gauge its diagnostic value in detecting smear-negative, Xpert-positive cases in Fiji.
Document Type: Research Article
Affiliations: 1: National Tuberculosis Program, Ministry of Health, Suva, Fiji 2: School of Population Health, The University of Queensland, Brisbane, Queensland, Australia
Publication date: September 21, 2014
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