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Open Access Sputum smear conversion and treatment outcomes for tuberculosis patients with and without diabetes in Fiji

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Settings: Three tuberculosis (TB) treatment centres under the Fiji National Tuberculosis Programme.

Objectives: To determine the prevalence of diabetes mellitus (DM) among TB patients for the period 2010–2012, and to evaluate sputum smear conversion and anti-tuberculosis treatment outcomes, comparing patients with and without DM.

Design: A retrospective descriptive study using routinely collected data from the TB register and in-patient folders.

Results: Of 577 TB patients identified, information on DM was available for 567 (98%), of whom 68 (12%) had DM. Smear status at 2 months was available for 254 (82%) patients with sputum smear-positive pulmonary TB. The sputum smear conversion rate (from positive to negative) was equivalent in TB patients with and without DM (78% vs. 80%, P = 0.66). Anti-tuberculosis treatment outcome information was available for 462 patients; the difference in outcome comparing successfully treated patients with those unsuccessfully treated was not statistically significant (91% in TB patients with DM vs. 84% in TB patients without DM, P = 0.06).

Conclusion: DM is common among TB patients in Fiji. Sputum smear conversion rates were not different in TB patients with and without DM; no difference in treatment success between the two groups was observed.
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Keywords: Fiji; diabetes mellitus; treatment outcomes; tuberculosis

Document Type: Research Article

Affiliations: 1: College of Medicine, Nursing and Health Sciences, Fiji National University, Suva, Fiji 2: National Tuberculosis Programme, Fiji Ministry of Health, Suva, Fiji 3: Public Health Division, Secretariat of the Pacific Community, Nouméa, New Caledonia, National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT, Australia

Publication date: September 21, 2014

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