Evaluation of recorded video-observed therapy for anti-tuberculosis treatment
METHODS: Patients aged ≥18 years who are currently receiving directly observed anti-TB treatment were invited to use VDOT for monitoring treatment. Pre- and post-treatment interviews and medical records were used to assess site differences in treatment adherence and patient characteristics and perceptions.
RESULTS: Participants were enrolled in New York City, NY (n = 48), San Diego, CA (n = 52) and San Francisco, CA, USA (n = 49). Overall, the mean age was 41 years (range 18–87); 59% were male; most were Asian (45%) or Hispanic/Latino (30%); and 77% were foreign-born. The median fraction of expected doses observed (FEDO) was 88% (IQR 76–96). At follow-up, 97% thought VDOT was “very or somewhat easy to use” and 95% would recommend VDOT to other TB patients. Age, race/ethnicity, annual income, and country of birth differed by city (P < 0.05), but FEDO and VDOT perceptions did not.
CONCLUSIONS: TB programs in three large US cities observed a high FEDO using VDOT while minimizing staff time and travel. Similar findings across sites support VDOT adoption by other large, urban TB programs.
Document Type: Research Article
Affiliations: 1: Division of Epidemiology, School of Medicine, University of California, San Diego, CA 2: Division of Biostatistics and Bioinformatics, School of Medicine, University of California, San Diego, CA 3: Department of Biological Sciences, University of Arkansas, Fayetteville, AR 4: San Diego County Health and Human Services Agency, San Diego, CA 5: Bureau of Tuberculosis Control, New York City Department of Health and Mental Hygiene, Queens, NY 6: San Francisco Department of Public Health, San Francisco, CA 7: Department of Epidemiology, University of Washington School of Public Health, Seattle, WA 8: Qualcomm Institute, Calit2, San Diego Division, University of California, San Diego, CA, USA
Publication date: May 1, 2020
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