Risk of tuberculosis during pregnancy in Mongolia, a high incidence setting with low HIV prevalence
DESIGN: We retrospectively collected data on pregnant women diagnosed with TB during 2013. Data were collected through doctors at central TB dispensaries who extracted the relevant information from patients' clinical records.
RESULTS: The overall incidence of TB among pregnant women was 228 (95%CI 187–276) per 100 000 person-years, resulting in an incidence rate ratio of 1.31 (95%CI 1.08–1.59) in pregnant women compared to the general population. Twelve per cent of the pregnant women with TB chose to have an abortion.
CONCLUSIONS: In this study, pregnant women had a 1.3-fold higher risk of developing TB than the general population. Based on a moderately increased risk of TB during pregnancy in our study and the potential for adverse health outcomes, TB screening among pregnant women can currently be justified, but the cost-effectiveness of this intervention remains unclear. Patients and doctors need to be educated about the safety of standard TB treatment in pregnancy to reduce the rate of abortions.
Document Type: Research Article
Affiliations: 1: National Tuberculosis Programme of Mongolia, Ulaanbaatar, Mongolia 2: Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia 3: Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia; South Western Sydney Clinical School, University of New South Wales, Sydney, New South Wales, Australia
Publication date: December 1, 2016
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