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Home / The International Journal of Tuberculosis and Lung Disease, Volume 20, Number 2

Tuberculosis treatment outcomes among peri-urban children receiving doorstep tuberculosis care

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OBJECTIVE: To determine the optimal tuberculosis (TB) management strategy for children living in peri-urban, resource-limited settings.

DESIGN: We compared TB treatment outcomes among children aged 0–15 years receiving doorstep care (n = 82) with those of a historical group (n = 97) receiving clinic-based care.

RESULTS: The doorstep care and clinic-based groups had similar age and sex profiles; treatment default rates were 3.7% (3/82) vs. 38.1% (37/97, P < 0.0001), treatment completion rates were 65.9% (54/82) vs. 51.6% (50/97, P = 0.01), and cure rates were 13.4% (11/82) vs. 2.1% (2/97), respectively (P < 0.0001).

CONCLUSION: Children living in peri-urban communities had improved TB treatment outcomes with doorstep care.

Keywords: South Africa; TB; doorstep care; peri-urban; tuberculosis

Document Type: Research Article

Affiliations: 1: *Centre for the AIDS Programme of Research in South Africa (CAPRISA) 2: *Centre for the AIDS Programme of Research in South Africa (CAPRISA), †Medical Research Council CAPRISA HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

Publication date: 01 February 2016

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  • The International Journal of Tuberculosis and Lung Disease (IJTLD) is for clinical research and epidemiological studies on lung health, including articles on TB, TB-HIV and respiratory diseases such as COVID-19, asthma, COPD, child lung health and the hazards of tobacco and air pollution. Individuals and institutes can subscribe to the IJTLD online or in print – simply email us at [email protected] for details.

    The IJTLD is dedicated to understanding lung disease and to the dissemination of knowledge leading to better lung health. To allow us to share scientific research as rapidly as possible, the IJTLD is fast-tracking the publication of certain articles as preprints prior to their publication. Read fast-track articles.

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