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The role of chest radiography in the suspicion for and diagnosis of pulmonary tuberculosis in intensive care units

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BACKGROUND: The role of chest radiography (CXR) in the clinical diagnosis and suspicion of pulmonary tuberculosis (PTB) remains uncertain in the intensive care unit (ICU) setting.

DESIGN: This case-control study compared the radiographic findings between ICU patients with and without co-existing PTB to define any predictive patterns for the diagnosis of PTB. Further analysis aimed to elucidate the impact of CXR on the clinical suspicion of PTB.

RESULTS: Eighty-nine (89) patients with PTB and an equal number of matched controls were evaluated. Consolidation was the most frequent radiographic pattern. There were no specific predictors for diagnosing PTB in the ICU. Of 89 patients, 55 (62.9%) had a delay in clinical suspicion of PTB. The time from ICU admission to TB diagnosis was significantly delayed in the group without clinical suspicion (30.7 vs. 5.3 days, P < 0.001). In multivariate analysis, a history of PTB was significantly associated with the clinical suspicion of PTB (OR 7.94, P = 0.012), but CXR patterns were not.

CONCLUSION: CXR does not contribute as much as expected in the clinical diagnosis and suspicion of PTB in the ICU setting.

Keywords: chest radiography; intensive care unit; pulmonary tuberculosis

Document Type: Regular Paper

Affiliations: 1: Departments of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan 2: Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan 3: Department of Nursing, Chang Gung Institute of Technology, Tao-Yuan, Taiwan

Publication date: 01 November 2009

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  • The International Journal of Tuberculosis and Lung Disease (IJTLD) is for clinical research and epidemiological studies on lung health, including articles on TB, TB-HIV and respiratory diseases such as COVID-19, asthma, COPD, child lung health and the hazards of tobacco and air pollution. Individuals and institutes can subscribe to the IJTLD online or in print – simply email us at [email protected] for details.

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