Skip to main content
padlock icon - secure page this page is secure

Free Content Drug resistance and HIV co-infection among pulmonary tuberculosis patients in Haiphong City, Vietnam

Download Article:
(PDF 230.2 kb)
SETTING: Vietnam is one of the 22 countries with the highest burden of tuberculosis (TB). Although its National Tuberculosis Programme (NTP) is effective, there is no ongoing surveillance of drug resistance.

OBJECTIVE: To establish the first step of a surveillance programme on anti-tuberculosis drug resistance in Haiphong, the third largest city in Vietnam.

DESIGN: A regional survey using proportionate cluster sampling in 2006, and recording patients' characteristics, including human immunodeficiency virus (HIV) co-infection.

RESULTS: There was a high prevalence of HIV co-infection (14.2%) among culture-positive pulmonary TB patients. The prevalence of drug resistance was high, and it was much higher among previously treated cases than among new cases (52.5% vs. 25.6%), with resistance to streptomycin being the most prevalent. The prevalence of multidrug resistance was high among new cases (4.4%), but was relatively low among previously treated cases (10%). HIV co-infection was related to resistance to rifampicin alone among new cases, but was not a risk factor for any other resistance pattern.

CONCLUSION: These results suggest a high prevalence of anti-tuberculosis drug resistance and of HIV co-infection among TB patients in Haiphong. Ongoing surveillance to assess resistance trends is needed, and the NTP needs to coordinate HIV and TB programmes to address the growing issue of TB and HIV co-infection.
No Reference information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics

Keywords: HIV; Vietnam; resistance; surveillance; tuberculosis

Document Type: Regular Paper

Affiliations: 1: Haiphong Medical School, Haiphong City, Vietnam 2: National Reference Laboratory, National Hospital of Tuberculosis and Respiratory Diseases, Hanoi, Vietnam

Publication date: July 1, 2008

More about this publication?
  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • International Journal of Tuberculosis and Lung Disease
  • Public Health Action
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more