Pregnancies complicated by multidrug-resistant tuberculosis and HIV co-infection in Durban, South Africa [Short Communication]
OBJECTIVE: To study the impact of multidrug-resistant tuberculosis (MDR-TB) and human immunodeficiency virus-1 (HIV-1) co-infection during pregnancy on maternal and perinatal outcome.
DESIGN: Prospective study performed between 1996 and 2001. Symptomatic pregnant women were investigated for TB. Those with confirmed MDR-TB were reported on.
RESULTS: Three of five pregnant women with MDR-TB were HIV-1 co-infected. One woman decided to terminate the pregnancy and one experienced pre-term labour. Two neonates had features of growth restriction.
CONCLUSION: Management of pregnant women with MDR-TB in an HIV-endemic area is possible in developing countries.
Document Type: Short Communication
Affiliations: 1: Centre for the AIDS Programme of Research in South Africa (CAPRISA), Nelson R Mandela School of Medicine, University of KwaZulu Natal, Congella, Durban, KwaZulu Natal, South Africa 2: Neonatal Unit, New Cross Hospital, Wolverhampton, West Midlands, UK 3: Women's Health and HIV Research Unit, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Congella, KwaZulu Natal, South Africa 4: King George V Hospital, Durban, KwaZulu Natal, South Africa
Publication date: June 1, 2007
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