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Paper Microfluidics as an Enabling Platform for Low-Cost Diagnostics

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Novel technologies are needed to address the urgent healthcare requirements of patients in the developing world and other resource-limited settings. Diagnostic devices that provide critical patient information at the point of need play a key role in the treatment and monitoring of disease. Such devices must be robust, simple to use, actionable, and extremely low in cost. Paper and other porous media provide an attractive platform from which to build devices that are able to address these needs. In an effort to expand the capabilities of porous media in diagnostics, we present a novel platform based on patterned paper microfluidic devices. In particular, 3-dimensional devices formed by stacking multiple layers of patterned paper provide the ability to perform many fluidic handling operations including: filtration; splitting; mixing; incubation; capture; and separations. Diagnostics For All (DFA) is developing tests based on this platform, in order to provide highly-functional diagnostic devices at unprecedented low cost. In this presentation, we will describe some specific examples of paper-based tests designed specifically for use in resource-poor areas.
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Document Type: Research Article

Publication date: January 1, 2012

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  • For more than 30 years, IS&T's series of digital printing conferences have been the leading forum for discussion of advances and new directions in 2D and 3D printing technologies. A comprehensive, industry-wide conference that brings together industry and academia, this meeting includes all aspects of the hardware, materials, software, images, and applications associated with digital printing systems?particularly those involved with additive manufacturing and fabrication?including bio-printing, printed electronics, page-wide, drop-on-demand, desktop and continuous ink jet, toner-based systems, and production digital printing, as well as the engineering capability, optimization, and science involved in these fields. In 2016, the conference changed its name formally to Printing for Fabrication to better reflect the content of the meeting and the evolving technology of printing.

    Please note: For purposes of its Digital Library content, IS&T defines Open Access as papers that will be downloadable in their entirety for free in perpetuity. Copyright restrictions on papers vary; see individual paper for details.

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