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Home / Folia Biologica (Kraków), Volume 53, Numbers 3-4

Free Content Implantation of Natural Hydroxyapatite from Porcine Bone into Soft Tissues in Mice

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The natural origin of hydroxyapatite (HA) derived from pig bones (Polish patent No.P-359 960 pending from 5th May 2003) was histologically examined for its biocompatibility following implantation into mouse muscles. The implanted ceramic was encapsulated by well vascularized connective tissue and very slowly resorbed by multinucleated cells. This material did not elicit an immune reaction and adjacent bones were unaffected. This ceramic could be safely used as a filling material alone, or as a composite graft.

Keywords: BIOCOMPATIBILITY; HYDROXYAPATITE; IMPLANTATION; MULTINUCLEAR CELLS; PORCINE; SYMPLASTS

Document Type: Research Article

Publication date: 2005

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  • Folia Biologica (Kraków) is an international online open access journal accepting original scientific articles on various aspects of zoology: evolution, ecology, genetic diversity, and experimental zoology.

    Publication in Folia Biologica (Kraków) is free of charge, the language of publication is English, and all papers are subject to peer reviews.

    Indexed by Journal Citation Reports (JCR) including Impact Factor (IF), Scopus, IC Journals Master List, and Polish Ministry of Science and Higher Education (currently awarded 100 points).

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    http://www.isez.pan.krakow.pl/en/folia-biologica.html

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