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Vitamin D – the prohormone among the vitamins Vitamin D – das Prohormon unter den Vitaminen

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Vitamin D is widely known as regulator of calcium homeostasis. It stimulates calcium uptake from the gut and increases the calcium concentration in the blood. Vitamin D stimulates the innate immune response and inhibits the adaptive immune system. Intervention studies with vitamin D suggest that intake of vitamin D has no significant therapeutic effect on chronic diseases such as diabetes, cancer, high blood pressure, cardiovascular and renal complications. However, it was found that vitamin D intake reduces the overall mortality and strengthens the resistance to acute infections.

German
Vitamin D ist als Regulator des Calcium-Stoffwechsels bekannt. Es erhöht die Calciumresorption aus dem Darm und steigert den Calciumspiegel im Blut. Vitamin D stimuliert die angeborene Immunantwort und inhibiert das adaptive Immunsystem. Interventionsstudien mit Vitamin D deuten allerdings darauf hin, dass die Gabe von Vitamin D keine signifikanten therapeutischen Effekte bei chronischen Erkrankungen wie Diabetes, Tumoren, Hypertonie, kardiovaskulären und renalen Komplikationen aufweist. Allerdings reduziert die Vitamin-D-Gabe bei Vitamin-D-Mangel die Gesamtmortalität und verbessert die Immunabwehr bei akuten Infektionen.
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Language: German

Document Type: Miscellaneous

Publication date: March 1, 2019

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