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Open Access Coulometric titration of ketotifen in tablets

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A method for the determination of ketotifen involving its reaction with iodine in an alkaline medium is presented. In coulometric titration using biamperometric end-point detection 0.25–2 μmol (77–618 μg) of ketotifen was successfully determined. The elaborated method was applied to the determination of ketotifen in drugs.

Document Type: Short Communication

Affiliations: 1: Department of Instrumental Analysis, University of Łódź, ul. Pomorska 163, Łódź, PL-90-236, Poland, Email: [email protected] 2: Department of Instrumental Analysis, University of Łódź, Łódź, Poland 3: Technical Chemistry School, Zgierz, Poland

Publication date: 01 March 2005

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  • Pharmazie is a leading journal in the field of pharmaceutical sciences. As a peer-reviewed scientific journal, Pharmazie is regularly indexed in the relevant databases like Web of science, Journal Citation Reports and many others. The journal is open for submissions from the whole spectrum of pharnaceutical sciences including Pharmaceutical Chemistry, Experimental and Clinical Pharmacology, Drug Analysis, Pharmaceutics, Pharmaceutical Biology, Clinical Pharmacy etc.
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