BACKGROUND: Urethral warmer and cryoheater are invented and applied in cryoablation to overcome urethral cryoinjury, but these devices cannot be fixed and precisely control the released heat which excessively reduces the effective ablation area. Current warmers enlarge the operation
difficulty and decrease the precision in temperature control. OBJECTIVE: A reformed catheter termed urethral heater aims to protect the urethra and simultaneously control the released heat so as to meet the aid of doctors' convenient operation in effective therapy, device fixation and
precise heat controllability. MATERIALS AND METHODS: In this paper, the temperature controller combined with temperature monitor was used to control the heating behavior of the urethral heater with the initial active temperature. The controllability and thermal protection of the urethral
heater was simulated and tested, which compared with that of urethral warmer. RESULTS: During the trials in vitro, the lowest temperature at the urethra surface is -3.7°C when one cryoprobe was introduced in the cryoablation for 15 min and -15.3°C with two cryoprobes.
Above all, the effective cryoablation area increased with the decline of initial active temperatures. CONCLUSION: The urethral heater is able to prevent the urethra from irreversible damage and modulate the ablation area. The delay of heat is a new way to decline the recurrence rate
and facilitate the desire of aconuresis during the cryoablation.
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Keywords:
CATHETER;
CRYOABLATION;
IMMUNE RESPONSE;
TEMPERATURE CONTROLLABILITY;
URETHRAL HEATER
Document Type: Research Article
Publication date:
01 July 2017
More about this publication?
CryoLetters is a bimonthly international journal for low temperature sciences, including cryobiology, cryopreservation or vitrification of cells and tissues, chemical and physical aspects of freezing and drying, and studies involving ecology of cold environments, and cold adaptation
The journal publishes original research reports, authoritative reviews, technical developments and commissioned book reviews of studies of the effects produced by low temperatures on a wide variety of scientific and technical processes, or those involving low temperature techniques in the investigation of physical, chemical, biological and ecological problems.