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Free Content Cryosurgery - a Review of Recent Advances and Current Issues

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Advances in cryosurgery since 1990 were initiated by the development of improved cryosurgical equipment and by the availability of intraoperative ultrasound to monitor the tissue-freezing process. Interest in research on the effects of freezing on tissue and on new clinical applications was then stimulated. The research led to a better understanding of the mechanisms of cryogenic injury, including cell death by apoptosis, which has emerged as a potential key to the use of adjunctive chemotherapy in the treatment of cancer. Optimization of cryosurgical technique will also improve clinical results.

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Keywords: CRYOSURGERY. CRYOTHERAPY. APOPTOSIS. NECROSIS

Document Type: Research Article

Publication date: March 1, 2002

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  • CryoLetters is a bimonthly international journal for low temperature sciences, including cryobiology, cryopreservation or vitrification of cells and tissues, chemical and physical aspects of freezing and drying, and studies involving ecology of cold environments, and cold adaptation

    The journal publishes original research reports, authoritative reviews, technical developments and commissioned book reviews of studies of the effects produced by low temperatures on a wide variety of scientific and technical processes, or those involving low temperature techniques in the investigation of physical, chemical, biological and ecological problems.

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