Antinociceptive Activity of Lectins from Diocleinae Seeds on Acetic Acid-Induced Writhing Test in Mice
Diocleinae lectins administered per oral route in mice inhibited the abdominal constrictions induced by acetic acid. The percentage of the lectins antinociception varied from 61% for Canavalia grandiflora (ConGf) to 20% for Dioclea violacea. ConGf inhibited contortions at all doses tested but not in a dose-dependent manner, involving carbohydrate recognition.
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Document Type: Research Article
Publication date: September 1, 2009
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