Skip to main content
padlock icon - secure page this page is secure

Research Progress of Axl Inhibitors

Buy Article:

$68.00 + tax (Refund Policy)

Axl, a Receptor Tyrosine Kinase (RTK) belonging to the TAM (Axl, Mer, Tyro3) family, participates in many signal transduction cascades after mostly being stimulated by Growth arrestspecific 6(Gas6). Axl is widely expressed in many organs, such as macrophages, endothelial cells, heart, liver and skeletal muscle. Over-expression and activation of Axl are associated with promoting chemotherapy resistance, cell proliferation, invasion and metastasis in many human cancers, such as breast, lung, and pancreatic cancers. Therefore, the research and development of Axl inhibitors is of great significance to strengthen the means of cancer treatment, especially to solve the problem of drug resistance. Axl inhibitors have attracted more and more researchers' attention in recent years. This review discusses the research progress of Axl inhibitors in recent years.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Axl; Cancer; Drug resistance; Gilteritinib; Natural products; Targeted therapy

Document Type: Review Article

Publication date: June 1, 2019

This article was made available online on July 1, 2019 as a Fast Track article with title: "Research Progress of Axl Inhibitors".

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more