Novel Classes of Antibacterial Drugs in Clinical Development, a Hope in a Post-antibiotic Era
Under this scenario, it is urgent to generate the most novel strategies for the development of antibacterial compounds with new targets or mechanism of action, without a structural relationship with the antibiotic drugs predecessors. Under this look, the present review addresses the development of the latest antibacterial drugs in clinical phases II and III, analyzing the design strategies by which these new molecules were obtained and the structure-activity relationship of these new families of antibiotics, in order to define the state of the vanguard antibacterial drugs in the post-antibiotic era.
Document Type: Review Article
Publication date: May 1, 2018
This article was made available online on August 28, 2018 as a Fast Track article with title: "Novel Classes of Antibacterial Drugs in Clinical Development, a Hope in a Post-antibiotic Era".