Skip to main content
padlock icon - secure page this page is secure

18F-Containing Positron Emission Tomography Probe Conjugation Methodology for Biologics as Specific Binders for Tumors

Buy Article:

$68.00 + tax (Refund Policy)

Molecular imaging can be used to evaluate the spatial–time change of the molecular biological phenomenon of the cell–molecule level in living bodies. Molecular imaging technology is expected to be applied in the fields of drug development, clinical diagnosis, and life science research. Specifically, positron emission tomography (PET) is a powerful non-invasive imaging technology for investigating physiological parameters in living animals using compounds labeled with PET radioisotopes as molecular probes. This review summarizes and compares various 18F-conjugation techniques that employ the chemical and enzymatic reactions of different types of tumor-targeting biological molecules such as peptides, proteins, antibodies, and nucleic acids.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Antibody; Biologics; Biopharmaceutics; Chemical reaction; Chemoenzymatic reaction; Click chemistry; Fluorine-18 (18F); Oligonucleotide; Peptide; Positron emission tomography (PET) probe; Protein; Tumor targeting

Document Type: Research Article

Publication date: October 1, 2016

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more