Skip to main content
padlock icon - secure page this page is secure

Recent Advances in the Discovery of Selective and Non-Selective 5-HT1D Receptor Ligands

Buy Article:

$68.00 + tax (Refund Policy)

This article highlights recent advances in the discovery of new agonists, antagonists and partial agonists of the 5-HT1D receptor. The field of 5-HT1D agonists continues to deliver a number of new potential therapeutic agents, although advances in this field are now more focussed on the clinical evaluation phase. The identification of novel compounds is greater for the 5-HT1D receptor antagonists, and whilst few truly selective ligands have been identified, a number of approaches are discussed towards defined mixed-pharmacology profiles. An overview is also given of recent advances in biological and clinical understanding of the receptor.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: 5-HT receptor; 5-HT1D agonist; 5-HT1D antagonist; serotonin receptor

Document Type: Research Article

Affiliations: Neuroscience CEDD, GlaxoSmithKline, New Frontiers Science Park, Third Avenue, Harlow, Essex, CM19 5AW, United Kingdom.

Publication date: April 1, 2010

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more