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Aerosol Drug Delivery Through High Flow Nasal Cannula

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Background: High flow nasal cannula (HFNC) is widely utilized to support critically ill adults, pediatrics and neonates. Through the continuous delivery of oxygen at high flow rates that meet or exceed patients' inspiratory flow, HFNC improves oxygenation, respiratory rates, patient comfort, and tolerance during therapy. As HFNC becomes more widely employed, clinicians have started to consider aerosol drug delivery through HFNC.

Conclusion: Using HFNC along with nebulizers as a potential therapy in aerosol medicine is a new and innovative approach for aerosol drug delivery to patients with pulmonary diseases.

The purpose of this paper is to review current in vitro and in vivo studies on aerosol drug delivery through HFNC in adults and children.

Keywords: Aerosols; adults; high flow nasal cannula; nebulizers; neonates; pediatrics

Document Type: Review Article

Publication date: 01 September 2017

This article was made available online on 17 January 2018 as a Fast Track article with title: "Aerosol Drug Delivery Through High Flow Nasal Cannula".

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  • Current Pharmaceutical Biotechnology aims to cover all the latest and outstanding developments in Pharmaceutical Biotechnology. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics in both pre-clinical and clinical areas of Pharmaceutical Biotechnology. Current Pharmaceutical Biotechnology is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments.
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