Skip to main content
padlock icon - secure page this page is secure

Multi-templates Molecularly Imprinted Polymer for the Specific Solid- Phase Extraction of Saponins from Panax notoginseng Herbal Extract

Buy Article:

$68.00 + tax (Refund Policy)

A novel multi-templates molecularly imprinted polymer (MIP), using three saponins mixture (notoginsenoside R1 (R1), ginsenoside Rg1 (Rg1) and ginsenoside Rb1 (Rb1)) as the template, was synthesized by precipitation polymerization and used as the solid-phase extraction (SPE) sorbent. The synthesis was optimized by using different functional monomers, polymerization solvents, cross-linkers, and molar ratios of template:functional monomer:cross-linker. The resulting MIPs were evaluated by transmission electron microscope (TEM) and adsorption experiments, exhibiting uniform spherical morphology, high adsorption capacity and rapid kinetics for the rebinding of template. The adsorption capacity of the imprinted polymers to the template was more than 2.0-folds that of non-imprinted polymers (NIPs). MIPs were successfully applied to the SPE for the extraction of R1, Rg1 and Rb1 from the Panax notoginseng herb extract. Mean recoveries of R1, Rg1 and Rb1 determined by HPLC (highperformance liquid chromatography) were in the range of 80.7–82.4% with relative standard deviations (RSDs) less than 3.2%. These results reveal that the multi-templates MIPs as SPE sorbent have good applicability to selectively extract a group of saponins from complex samples.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Ginsenoside Rg1; Panax notoginseng; ginsenoside Rb1; multi-templates molecularly imprinted polymer; notoginsenoside R1; precipitation polymerization; solid-phase extraction

Document Type: Research Article

Publication date: November 1, 2015

More about this publication?
  • Current Pharmaceutical Analysis publishes authoritative reviews, written by experts in the field on all the most recent advances in pharmaceutical and biomedical analysis. All aspects of the field are represented including drug analysis, analytical methodology and instrumentation. The journal is essential to all involved in pharmaceutical, biochemical and clinical analysis.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more