Anti-cancer Nitrogen-Containing Heterocyclic Compounds
Cancer is one of the leading causes of death worldwide. Mutation of the cell regulates genes and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the current therapy of cancer despite their side effects. The general area of research relates to heterocyclic
chemistry. The purpose of the article is to review the most recent advances in nitrogen-containing heterocyclics as possible chemotherapy agents for cancer. More than 90% of the novel drugs bear heterocyclics and among them, nitrogencontaining heterocyclic compounds show superior pharmaceutical
effect than non-nitrogen compounds. Nitrogen-containing compounds, the heart of drug discovery, present a significant and valuable group of molecules that play a chief and vital role in the metabolism of living cells.
Keywords: Anticancer; chemotherapy agents; heterocyclic; natural nitrogen-containing heterocyclic; nitrogen-containing heterocyclic; synthetic nitrogencontaining heterocyclic
Document Type: Review Article
Publication date: 01 October 2018
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