Preparation of Acridine Derivatives Bearing Saturated Rings
This review presents possible routs of preparation of acridine derivatives con-taining saturated rings that can be obtained both as a result of traditional organic synthesis based on cyclization and condensation reactions and whenever available by partial or total catalytic (heterogeneous
or homogeneous) hydrogenation of appropriate acridine derivatives. Methods of preparations of acridine derivatives bearing saturated rings are presented and discussed. The influence of resonance stabilisation energies of N-heteroaromatic and partly saturated N-heteroaromatic structures on
hydrogenation susceptibility is discussed in relation to other aspects influencing saturation N-heteroaromatic versus carbocyclic rings.
Keywords: Acridine; acridine derivatives; catalytic heterogeneous hydrogenation; catalytic homogeneous hydrogenation; condensation reactions; resonance stabilisation energy; selective hydrogenation
Document Type: Research Article
Publication date: 01 January 2017
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