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The Fabrication and Application of Bio-Functional Microspheres

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Bio-functional microspheres (BFMs), including drug carrier microspheres, fluorescence microspheres, magnetic microspheres, immune microspheres, enzyme immobilization microspheres, solid-phase synthesis microspheres, and molecular imprinting microspheres, are core-shell microspheres containing bio-molecules and functional materials in their structures. Because of the presence of core-shell structures and spherical shapes, BFMs bear many unique functions and fascinating properties. The research on BFMs has surprisingly blossomed during recent decades. In this review, we give a systematic, balanced and comprehensive summary of the main aspects of BFMs related to their preparation and application, and propose perspectives for future developments of BFMs.
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Keywords: Bio-function; enzyme immobilization; fluorescence; immunity; microspheres

Document Type: Research Article

Publication date: September 1, 2014

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