Skip to main content
padlock icon - secure page this page is secure

BSA and DNA Binding Studies of Aspergillus foetidus Mediated Biosynthesized CdS Nanoparticles

Buy Article:

$68.00 + tax (Refund Policy)

Background: Instead of traditional antibiotics, antimicrobial property of nanoparticle has been documented in various research reports. In such cases, nanoparticle mainly interacts with proteins and DNA like macromolecules. But still the mechanism of anti-microbial activity of CdS nanoparticles is partially known.

Methods: We have synthesized CdS nanoparticles by using Aspergillus foetidus (MTCC8876). Our process for synthesis of nanoparticle is hazard free as well as economic. To investigate the mode of interaction between CdS nanoparticles and BSA, a number of photo- and fluorometric analyses were considered. Furthermore, DNA (calf thymus DNA) binding ability of CdS nanoparticles was also studied through photo- and fluorometric analyses and viscosity measurement.

Results: About 10-15 nm of stable CdS nanoparticle has been synthesized by Aspergillus foetidus. Our results ascertained that CdS nanoparticles interact with BSA (binding constant, K=13.8 104M−1) and DNA (binding constant, K=10.47 102M−1) successively.

Conclusion: Aspergillus foetidus mediated biosynthesized CdS nanoparticles effectively interact with BSA and calf thymus DNA.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Aspergillus; Cadmium sulfide; DNA; Nanoparticles; Protein

Document Type: Research Article

Publication date: December 1, 2016

More about this publication?
  • Current Nanoscience publishes authoritative reviews and original research reports, written by experts in the field on all the most recent advances in nanoscience and nanotechnology. All aspects of the field are represented including nano- structures, synthesis, properties, assembly and devices. Applications of nanoscience in biotechnology, medicine, pharmaceuticals, physics, material science and electronics are also covered. The journal is essential to all involved in nanoscience and its applied areas.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more