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Nanoceria: Synthesis and Biomedical Applications

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Cerium oxide or ceria is an inorganic compound of Cerium, a rare earth element of lanthanide series. Due to the unique ability of cerium to switch oxidation states between +3 and +4 it has various applications as ultraviolet light absorbers, catalytic converters for automobile exhaust systems, solar cells, optics, oxygen sensors and other commercial and biomedical applications. Cerium oxide nanoparticles popularly known as nanoceria are efficient free radical scavengers and are considered as a potent therapeutic option for the treatment of ROS mediated disorders like neurodegenerative disorders, retinal disorders, cancer and can also act as a potent drug delivery agent. Engineered nanoparticles have the potential to revolutionize diagnosis and treatment of many diseases which require the synthesis of nanoceria with biocompatibility so as to enhance its therapeutic potential without inducing any cytotoxicity. Here we review the various methods for synthesis of nanoceria for biomedical applications and we discuss the challenges to realize the potential of nanoceria in therapeutics.
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Keywords: Antioxidants; biocompatibility; cytotoxicity; drug delivery; nanoceria; nanoparticle; therapeutics

Document Type: Research Article

Publication date: October 1, 2013

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  • Current Nanoscience publishes authoritative reviews and original research reports, written by experts in the field on all the most recent advances in nanoscience and nanotechnology. All aspects of the field are represented including nano- structures, synthesis, properties, assembly and devices. Applications of nanoscience in biotechnology, medicine, pharmaceuticals, physics, material science and electronics are also covered. The journal is essential to all involved in nanoscience and its applied areas.
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