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Otorhinolaryngological Manifestations in Sjogren Syndrome

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Background: Sjögren's Syndrome (SS) is the second most common autoimmune rheumatic disease after rheumatoid arthritis and affects approximately 1 to 3% of the population. Most patients affected by Sjogren's syndrome manifest otorhinolaryngological involvement, such as glandular, ocular, oral, otological, pharyngeal, laryngeal and sinonasal symptoms.

Objective: The aim of this article is to emphasize the otorhinolaryngological manifestations of SS. Since otorhinolaryngologists are often the first practitioners to detect the symptoms, a complete and careful ENT examination should be performed in all the patients suspected to have this syndrome.

Conclusion: To date, there is no straight forward and reliable diagnostic test for Sjögren's syndrome. Its diagnosis can be difficult because the signs and symptoms vary widely and sometimes are similar to those caused by other diseases. Hence, it is important to identify conditions with similar patterns in order to make a correct diagnosis, begin the appropriate therapy, determine a proper follow-up and ensure a good quality of life.

Keywords: Autoimmune disease; dry eye; parotid gland; salivary gland swelling; sjogren's syndrome; xerophthalmia; xerostomia

Document Type: Review Article

Publication date: 01 April 2018

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  • Current Immunology Reviews publishes frontier reviews on all the latest advances in clinical immunology. The journal's aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in clinical immunology.
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