Skip to main content
padlock icon - secure page this page is secure

Distinct Functions of Interleukin-10 Derived from Different Cellular Sources

Buy Article:

$68.00 + tax (Refund Policy)

The defense against microbial infection by innate and adaptive immune responses bears the intrinsic risk of immune-mediated inflammatory “collateral” damage to host tissue. The cytokine interleukin-10 plays a central role in the control mechanisms, which limit inflammatory responses in order to prevent immunopathology. This pleiotropic soluble factor can be produced by a broad spectrum of different cell types. Interestingly, efficient control of immune responses to different stimuli seems to require the release of IL-10 from different cellular sources. This review summarizes recent experiments demonstrating that production of IL-10 by different cell types can serve distinct and non-redundant functions in vivo.

No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Interleukin-10; TH1 responses; immune regulation; immunopathology; inflammation; innate immunity

Document Type: Research Article

Publication date: February 1, 2008

More about this publication?
  • Current Immunology Reviews publishes frontier reviews on all the latest advances in clinical immunology. The journal's aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in clinical immunology.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more