Conjugation Strategies for Colonic Delivery and its Application in Colorectal Cancer Therapy
Methods: Of all strategies, the conjugation of a model drug to a carrier (with or without spacers) has been recognized as promising for targeting the colon.
Results: This is because the conjugation method releases large amounts of the drug while reducing the amount of the drug released in the stomach and small intestine.
Conclusion: This review focuses on the design of linkage conjugates that carry out specific delivery to the colon. The types of conjugation for application in colorectal cancer therapy will be discussed as well.
Document Type: Review Article
Publication date: November 1, 2017
This article was made available online on November 13, 2017 as a Fast Track article with title: "Conjugation Strategies for Colonic Delivery and its Applicationin Colorectal Cancer Therapy".
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