Vasopressin and Terlipressin in Neonates and Children with Refractory Septic Shock
However, the pharmacology of vasopressin/terlipressin in newborns and children has not been sufficiently investigated and data on potential short and long-term adverse effects are still lacking. Further clinical, pharmacokinetic and pharmacodynamic studies are needed to better define the role of vasopressin and terlipressin in septic shock, as well as to prove their effectiveness and safety in infants and children.
Keywords: AVP; Catecholamin; Hypothalamus; Neonates; Perfusion; Refractory Septic Shock; Renal blood flow; Vasoconstriction; Vasopressin; child; pharmacodynamics; pharmacokinetics; receptors; septic shock; terlipressin
Document Type: Research Article
Publication date: February 1, 2013
- Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:
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