Roles of Mitogen-Activated Protein Kinases in the Regulation of CYP Genes
Keywords: 26S proteasome; Aryl hydrocarbon receptor; CAATT-enhancer binding protein; CYP Genes; CYP gene regulation; Cytochrome P450; Extracellular signal-regulated kinas; Hepatocyte nuclear factor; Interleukin; MAP kinases; Mitogen-Activated Protein Kinases; P450; Roles of Mitogen-Activated Protein Kinases in the Regulation of CYP Genes; Sterol Biotransformation; adrenocorticotropic hormone; androgen; angiotensin-II; basic leucine-zipper transcription factors; cellular stress; chenodeoxycholic; coactivators; corepressors; deoxycholic acids; environmental stimuli; epoxygenase gene; es-tradiol; estrogen; ex-ogenous stimuli; glucocorticoid; hepatic nuclear; hypoxia; lithocholic; mineralocor-ticoid receptors; nuclear receptors; oxysterol substrates; pathological stimuli; phosphorylation; posed to nitrative stress induced by; progestin; proteolysis; transcription factors; ubiquitin-directed; xenobiotics
Document Type: Research Article
Publication date: 01 December 2010
- Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:
In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts. - Editorial Board
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