Molecular Determinants of Fluoroquinolone Antibacterial Agents Pharmacokinetics
This review presents the published data regarding the molecular determinants (enzymes, transporters, orphan nuclear receptors) of fluoroquinolones pharmacokinetics in humans. The clinical impact of these determinants (drug disposition, drug-drug interactions) is also discussed.
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Document Type: Research Article
Publication date: September 1, 2009
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