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Bioactive Cyclohexenones: A Mini Review

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Cyclohexenone derivatives have been found to play pivotal role in the field of medicinal chemistry. They are embedded in several bioactive natural products like carvotacetones, phorbasins, antheminones and gabosines which are well known anchor for their biological activity like antitumor, antiplasmodial, antileishmanial and other activities. Therefore, the reported biological activity of cyclohexenone derivatives is coupled up with explanation. This mini review article summarizes the biological potential of bioactive cyclohexenone derivatives and their mechanism of action reported over the past few decades.

Keywords: Antitumor; COTC; anticonvulsant; biological activities; cyclohex-2-enone

Document Type: Research Article

Publication date: 01 December 2015

More about this publication?
  • The journal aims to provide updates to researchers about new bioactive compounds with proven activities in various biological screenings and pharmacological models. The journal will contain information about the structures, biological activities and sources of chemical entities discovered or designed by researchers and published in leading journals. The aim is to provide a valuable information source of bioactive compounds synthesized or isolated, which can be used for further development of pharmaceuticals by industry and academia.

    The journal should prove to be essential reading for pharmacologists, pharmaceutical chemists and medicinal chemists who wish to be kept informed and up-to-date with the latest and most important developments about new bioactive compounds of natural or synthetic origin, including recent patents.
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