Skip to main content
padlock icon - secure page this page is secure

Harnessing Impaired Energy Metabolism in Cancer Cell: Small Molecule- Mediated Ways to Regulate Tumorigenesis

Buy Article:

$68.00 + tax (Refund Policy)

Altered cellular metabolism is a hallmark of tumorigenesis. Described first in 1924 by Otto Warburg, a cancer cell undergoes complete metabolic reprogramming to attain nutrient self-sufficiency for proliferation and survival. Interplay between diverse signalling cascades confers this metabolic advantage. In this review we focus on signalling molecules that regulate this altered metabolic paradigm in a cancer cell with emphasis on small molecule mediated intervention for attenuation of growth and progression of tumor.

No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Akt; Fibroblast growth factor receptor (FGFR); Hexokinase II; Myc; Pyruvate kinase; SGLT2 expression; Warburg effect; aerobic glycolysis; glutaminolysis; hypoxic tumor cells; isozymes; mTOR; mitochondrial outer membrane; tumor cell populations

Document Type: Research Article

Publication date: March 1, 2011

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more